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[11-2] 学术报告:Regulation of spermatogenesis by a local functional axis in the testis through cytoskeletal re-organization - an unexpected turn of events
  发布日期:2017-10-27  |  来源:干细胞与生殖生物学国家重点实验室  |      

  题目:Regulation of spermatogenesis by a local functional axis in the testis through cytoskeletal re-organization - an unexpected turn of events 

  报告人:Chuen Yan Cheng 教授(中国科学院动物研究所秉志论坛讲习教授,中国科学院海外评审专家) 

  邀请人:干细胞与生殖生物学国家重点实验室性腺生物学研究组  刘以训研究员 

  报告时间:2017年11月2日,上午 9:00 

  报告地点:动物所C101会议室 

  Director, Urology Research Center, University of Rochester,Rochester, NY 

  George Whipple Distinguished Professor, Departments of Pathology, Urology and Radiation Oncology, and The Cancer Center, University of Rochester, Rochester, NY. USA 

  PUBLICATIONS 

  1.  Chen, Haiqi; Mruk, Dolores D; Lui, Wing-Yee; Wong, Chris K C; Lee, Will M; Cheng, C Yan. Cell polarity and planar cell polarity (PCP) in spermatogenesis. Seminars in cell & developmental biology.2017 

  2. Chen, HQ [1] ; Mruk, DD [1] ; Lee, WM [2] ; Cheng, CY [1,2]. Regulation of spermatogenesis by a local functional axis in the testis: role of the basement membrane-derived noncollagenous 1 domain peptide. FASEB Journal. 2017, 31(8): 3587-3607 

  3. Gao, Y [1] ; Chen, HQ [1] ; Xiao, X [1,2] ; Lui, WY [3] ; Lee, WM [3] ; Mruk, DD [1] ; Cheng, CY [1].Perfluorooctanesulfonate (PFOS)-induced Sertoli cell injury through a disruption of F-actin and microtubule organization is mediated by Akt1/2. Scientific reports. 2017,7:1110 

  4. Gao, Y [1] ; Mruk, D [1] ; Chen, HQ [1] ; Lui, WY [2] ; Lee, WM [2] ; Cheng, CY [1]. Regulation of the blood-testis barrier by a local axis in the testis: role of laminin 2 in the basement membrane. FASEB Journal.2017,31(2) : 584-597 

  5. Gao, Y[1] ; Mruk, DD [1] ; Lui, WY[2] ; Lee, WM[2] ; Cheng, CY[1]. F5-peptide induces aspermatogenesis by disrupting organization of actin- and microtubule-based cytoskeletons in the testis.Oncotarget. 2016,7(39) : 64203-64220 

  6. Li, N [1] ; Mruk, DD [1] ; Mok, KW [1] ; Li, MWM [1] ; Wong, CKC [2] ; Lee, WM [3] ; Han, DS [4] ; Silvestrini, B [5] ; Cheng, CY [1]. Connexin 43 reboots meiosis and reseals blood-testis barrier following toxicant-mediated aspermatogenesis and barrier disruption. FASEB Journal. 2016,30(4): 1436-1452 

  7. Li, N [1] ; Tang, EI [1] ; Cheng, CY [1]. Regulation of blood-testis barrier by actin binding proteins and protein kinases. Reproduction.2016,151(3) : R29-R41 

  8. Mok, KW [1] ; Mruk, DD [1] ; Cheng, CY [1]. rpS6 regulates blood-testis barrier dynamics through Akt-mediated effects on MMP-9. Journal of cell science.2014,127(22) : 4870-4882 

  9. Xiao, X [1] ; Mruk, DD [1] ; Wong, CKC [2] ; Cheng, CY [1]. Germ Cell Transport Across the Seminiferous Epithelium During Spermatogenesis. PHYSIOLOGY.2014,29(4) : 286-298 

  10. Wan, HT [1] ; Mruk, DD [1] ; Tang, EI [1] ; Xiao, X [1] ; Cheng, YH [2] ; Wong, EWP [1] ; Wong, CKC [3] ; Cheng, CY [1]. Role of non-receptor protein tyrosine kinases in spermatid transport during spermatogenesis. Seminars in cell & developmental biology. 2014,30 : 65-74 

  11. Su, LL[1] ; Mruk, DD[1] ; Lie, PPY[1] ; Silvestrini, B[2] ; Cheng, CY [1]. A peptide derived from laminin-gamma 3 reversibly impairs spermatogenesis in rats. NATURE COMMUNICATIONS. 2012.3 


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