姓  名: 谭薇琦
学  科: 细胞生物学
电话/传真: +86-10-64807318 / 
电子邮件: tanwq@ioz.ac.cn
通讯地址: 北京市朝阳区大屯路甲3号院,中国科学院干细胞与再生医学创新研究院,中国科学院动物研究所 100101
更多信息: 免疫和信号传导研究组     

简历介绍:

谭薇琦,女,博士,副研究员。

1988年获北京大学学士学位,1996年获香港科技大学硕士学位,2005年获香港理工大学博士学位。2009年-2011年在美国MD Anderson Cancer Center做访问学者。研究方向是以小鼠和细胞作为研究系统,探讨microRNA甲基化对与疾病有关基因的调控机制。

研究领域:

社会任职:

获奖及荣誉:

承担科研项目情况:

科技部国家重点研发计划、国家自然科学基金面上项目、北京市自然科学基金面上项目。

代表论著:

  1. Cheng, Y.#, Wang, Z. M.#, Tan, W. #, Wang, X.#, Li, Y., Bai, B., Li, Y., Zhang, S. F., Yan, H. L., Chen, Z. L., Liu, C. M., Mi, T. W., Xia, S., Zhou, Z., Liu, A., Tang, G. B., Liu, C., Dai, Z. J., Wang, Y. Y., Wang, H., Wang, X., Kang, Y., Lin, L., Chen, Z., Xie, N., Sun, Q., Xie, W., Peng, J., Chen, D., Teng, Z. Q., and Jin, P. (2018) Partial loss of psychiatric risk gene Mir137 in mice causes repetitive behavior and impairs sociability and learning via increased Pde10a. Nat Neurosci 21, 1689-1703 (#, cofirst auther)
  2. Jin, W., Wang, L., Zhu, F., Tan, W., Lin, W., Chen, D., Sun, Q., and Xia, Z. (2016) Critical POU domain residues confer Oct4 uniqueness in somatic cell reprogramming. Sci Rep 6, 20818
  3. Tan, W., Gu, J., Huang, M., Wu, X., and Hildebrandt, M. A. (2015) Epigenetic analysis of microRNA genes in tumors from surgically resected lung cancer patients and association with survival. Mol carcinog 54 Suppl 1, E45-51
  4. Zhu, G., Li, Y., Zhu, F., Wang, T., Jin, W., Mu, W., Lin, W., Tan, W., Li, W., Street, R. C., Peng, S., Zhang, J., Feng, Y., Warren, S. T., Sun, Q., Jin, P., and Chen, D. (2014) Coordination of engineered factors with TET1/2 promotes early-stage epigenetic modification during somatic cell reprogramming. Stem cell reports 2, 253-261
  5. Hildebrandt, M. A., Tan, W., Tamboli, P., Huang, M., Ye, Y., Lin, J., Lee, J. S., Wood, C. G., and Wu, X. (2012) Kinome expression profiling identifies IKBKE as a predictor of overall survival in clear cell renal cell carcinoma patients. Carcinogenesis 33, 799-803 
  6. Tan, W., Hildebrandt, M. A., Pu, X., Huang, M., Lin, J., Matin, S. F., Tamboli, P., Wood, C. G., and Wu, X. (2011) Role of inflammatory related gene expression in clear cell renal cell carcinoma development and clinical outcomes. J Urol 186, 2071-2077
  7. Hildebrandt, M. A., Gu, J., Lin, J., Ye, Y., Tan, W., Tamboli, P., Wood, C. G., and Wu, X. (2010) Hsa-miR-9 methylation status is associated with cancer development and metastatic recurrence in patients with clear cell renal cell carcinoma. Oncogene 29, 5724-5728
  8. Tan, W., Wang, J. X., Lin, Z. Q., Li, Y. R., Lin, Y., and Li, P. F. (2008) Novel cardiac apoptotic pathway: the dephosphorylation of apoptosis repressor with caspase recruitment domain by calcineurin. Circulation 118, 2268-2276
  9. Tan, W., Wang, K., Lv, D.Y., and Li, P.F. (2008) Foxo3a inhibits cardiomyocyte hypertrophy through transactivating catalase. J Biol Chem 283, 29730-29739
  10. Tan, W., Gou, D. M., Tai, E., Zhao, Y. Z., and Chow, L. M. (2006) Functional reconstitution of purified chloroquine resistance membrane transporter expressed in yeast. Arch Biochem Biophys 452, 119-128

写给考生的话:

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